Discover the critical role of cell surface architecture for CAR T function and effectivenessÂ
CAR T cell potency, persistence, and efficacy are dictated not just by what proteins are expressed, but by how they are organized across the cell surface.Â
The Pixelgen Proxiome CAR portfolio extends the capability of our Proximity Network Assay to allow CAR-specific detection. It unlocks the analysis of protein organization within engineered CAR T and NK cell products and clinical samples.Â
Match the detection antibody to your specific CAR construct by targeting human FMC63, FLAG, G4S, and our recent expansion for Whitlow.Â
Four formats, one workflow
| Product | Validated for | Catalog No. |
| Pixelgen Proxiome FMC63 Barcoded Antibody v2 | FMC63-based CAR constructs | CAR102 |
| Pixelgen Proxiome FLAG Barcoded Antibody v2 | FLAG-tagged CAR constructs | CAR103 |
| Pixelgen Proxiome G4S Barcoded Antibody v2 | G4S-containing CAR constructs | CAR104 |
| Pixelgen Proxiome Whitlow Barcoded Antibody v2 | Whitlow-containing CAR constructs | CAR105 |
Effortless integration for a tailored cell surface architecture analysis
- Add-on to the Pixelgen Proxiome Kit v2, the antibodies are spiked-in seamlessly into the same workflow.
- Combine up to 2 CAR products in the same experiment, for samples that need more than one detection reagent.
- Compatible with the Pixelgen Proxiome Custom Conjugation Kit, so you can extend your panel with custom targets alongside CAR detection.
- Fully integrated into Pixelator, the standard analysis software for cell surface architecture profiling.
Product Sheet
Protein List
The FLAG, G4S, FMC63, and Whitlow barcoded antibodies are used as spike-ins for the Proxiome Immuno 155 panel, a pre-validated immunology panel spanning 155 protein targets and 3 controls. This way, you can allow CAR detection to sit alongside the rest of your immune profiling in a single run.