Cell surface proteins are proteins embedded in or spanning the layer of cell membranes. These proteins are integral to the way in which a cell interacts with the environment around it, including other cells.
Each Molecular Pixelation assays has been thoroughly evaluated and optimized to fit into a broad immunological multiplex panel.
Protein selection
The proteins that make up the structure of the panel have been selected based on feedback from thought leaders as well as in-depth literature evaluation.
One important part of the panel consists of the backbone proteins to distinguish between different immunological cell types.
A broad spectrum of proteins were also included with different abundance on the cell surface have been chosen. The highly abundant proteins serve as a connectivity baseline in order to ensure capturing also proteins with lower expression.
Well-known protein markers as well as more exploratory proteins have been included.
In addition, subsets of scientifically interesting targets not yet fully understood have also been included in the panel.
The majority of the panel is composed of markers expressed on:
